Antimicrobial Activity of Bacteria Associated with Sponge Xestospongiatestudinaria in Vietnam

International Journal of Development Research

Volume: 
09
Article ID: 
15570
5 pages
Research Article

Antimicrobial Activity of Bacteria Associated with Sponge Xestospongiatestudinaria in Vietnam

Abstract: 

Drug-resistant bacteria is spreading globally and threatening to human health. However, the number of novel antibiotics is decreasing gradually. Therefore, the strategies and studies for the discovery of novel antibiotics are essential to develop. Microorganisms associated with sponges are highly diverse and are one of the rich sources of bioactive compounds with different bioactive activity. In this study, we isolated 104 bacterial strains associated with the sponge Xestospongiatestudinaria, 20 of which exhibited antimicrobial activity against at least one of indicator microorganisms Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 25923, Bacillus subtilis ATCC 27212, Staphylococcus aureus ATCC 12222, Candida albicans ATCC 7754. Identification of antimicrobial strains based on the 16S rRNA gene sequence showed the activity strains belonged to six different genera, including Bacillus, Paenibacillus, Pseudomonas, Streptomyces, Vibrio, Pseudovibri. Our study revealed that sponge-associated bacteria from sponge are a potential source of antimicrobial compounds.

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