Drug interactions in patients affected by cardiovascular disease

International Journal of Development Research

Volume: 
10
Article ID: 
20153
3 pages
Research Article

Drug interactions in patients affected by cardiovascular disease

Lúcia Helena Almeida Gratão, Natália de Barros Teles, Sônia Lopes Pinto, Bernardete Weber and Guilherme Nobre L. do Nascimento

Abstract: 

This work aims to analyze the possible drug interactions in adults and elderly people with manifest atherosclerotic disease. Fifty patients were enrolled in the multi-center study of the Brazilian Cardioprotective Food Program, UFT, Palmas, Tocantins. The Drugdex (MicroMedex) and Med Tap software databases and the Drug Interactions website were used. We obtained an average of 6.4 medications per individual, and we observed the incidence of clinically relevant interactions such as Clopidogrel with AAS 38% and Enalapril with AAS 26%. Potentially dangerous interactions in clinical practice, such as Clopidogrel with ASA, can present health risks to patients and may even lead to death. Different interections were observed, from light to severe levels, thus requiring better care by the multi-professional health team with this type of patient, since these interactions may lead to greater appearance of side effects or loss effects of the drugs so necessary for the treatment of these individuals.

DOI: 
https://doi.org/10.37118/ijdr.20153.12.2020
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