Evaluation of the antimicrobial potential of actinomycetes isolated from mangrove soils in the municipality of São João de Pirabas, Pará, Brazil
International Journal of Development Research
Evaluation of the antimicrobial potential of actinomycetes isolated from mangrove soils in the municipality of São João de Pirabas, Pará, Brazil
Received 17th June, 2022; Received in revised form 20th July, 2022; Accepted 29th July, 2022; Published online 30th August, 2022
Copyright © 2022, José de Sena Gomes Júnior et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The present work aimed to characterize mangrove-derived actinomycetes strains isolated from São João de Pirabas mangrove in Pará State of Brazil and evaluate their antimicrobial action against clinical importance bacteria. Sixteen isolated actinomycetes strains were evaluated by their morphology and biochemical features and antibacterial activity against Staphylococcus aureus, Escherichia coli, Klebsiella sp. and Enterococcus faecalis. They presented mixed morphological characteristics and different biochemical profiles which reinforce diversification on mangrove-derived actinomycetes strains. Colony growth and pigment production were evaluated in Czapek Dox agar medium enriched with 0,5 nystatin which was satisfactory for this study. Also, the isolates showed high and interesting broad-spectrum antibacterial inhibition against pathogenic Gram-positive and Gram-negative bacteria leading nosocomial infections worldwide by the two confrontation methods employed. Based on these evidences, São João de Pirabas mangrove in Amazon tropical region is a rich and prospective source for actinomycetes owing important antibacterial compounds.
